Car Rental Santa Cruz de la Sierra

Search and Compare from Car Companies in Santa Cruz de la Sierra

I have a discount code

Featured car rental suppliers

Compare from agencies

car suppliers logo

  • protection illustration

    Change your mind

    Penalty-free cancellation on many/select car rentals
  • trophy illustration

    Treat yourself

    One Key members save 10% or more on over 1 million car rentals
    Learn about One Key
  • package illustration

    Shop smart

    Compare car suppliers and package your flight, hotel, and car to save

Top Car Deals in Santa Cruz de la Sierra

* Price found within the past 6 days. Click for updated prices.

Economy

Chevrolet Spark
  • 4 people
Santa Cruz de la Sierra, Extremadura, ESP
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus
  • 4 people
Santa Cruz de la Sierra, Extremadura, ESP
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla
  • 5 people
Santa Cruz de la Sierra, Extremadura, ESP
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass
  • 5 people
Santa Cruz de la Sierra, Extremadura, ESP
Jeep Compass
SUV Jeep Compass

Don't see what you're looking for?

See all car rentals in Santa Cruz de la Sierra
View all cars

What you need to know for your Santa Cruz de la Sierra car rental

Reasons to book a car rental in and around Santa Cruz de la Sierra

Renting a car in Santa Cruz de la Sierra is an excellent choice for travelers seeking freedom and flexibility to explore the area. With a rental car, you can easily navigate to key attractions such as the Plaza Mayor, the Statue of Francisco Pizarro, and the historic Juan Pizarro de Orellana Palace, all located 9 miles away from the city center. This convenience allows you to manage your luggage efficiently and create a travel itinerary that suits your preferences.

Additionally, a rental car enables you to visit nearby destinations like Trujillo, which is also 9 miles away and features the stunning Church of Santa Maria la Mayor Trujillo and Trujillo Castle. Puerto de Santa Cruz is just 2 miles away, offering more cultural experiences at the Plaza Mayor and other local landmarks. For those interested in wine and cheese, Ibahernando, located 4 miles away, provides attractions such as the Museo de Vino y Queso. Overall, a rental car ensures that you can explore these destinations comfortably and at your own pace, making it an ideal choice for both solo travelers and families alike.

Where to stay around Santa Cruz de la Sierra

  • Puerto de Santa Cruz: Located 2 miles from Santa Cruz de la Sierra, Puerto de Santa Cruz is a charming destination perfect for cultural exploration. Visitors can enjoy landmarks such as the Plaza Mayor, a central square ideal for relaxation and socializing. Additionally, the Statue of Francisco Pizarro and the historic Juan Pizarro de Orellana Palace offer a glimpse into the area's rich history, making it a great spot for those interested in culture.
  • Trujillo: About 9 miles from Santa Cruz de la Sierra, Trujillo is renowned for its cultural and adventure experiences. This historic city features the impressive Trujillo Castle, which is perfect for romantic getaways and cultural vacations. The Church of Santa Maria la Mayor Trujillo adds to the cultural charm, while the scenic Plaza Mayor serves as a delightful gathering place for tourists. Outdoor activities like birdwatching and swimming are also popular here, especially in favorable seasons.
  • Madronera: Just 8 miles from Santa Cruz de la Sierra, Madronera is an excellent choice for those seeking outdoor adventures and stunning scenery. Visitors can explore the local landmarks, including the Plaza Mayor and the historic Juan Pizarro de Orellana Palace. The area is known for its nature reserves and national parks, making it ideal for outdoor enthusiasts. Seasonal beauty can be appreciated throughout the year, especially during spring and fall when the landscapes are particularly vibrant.

10 tips to save on your car rental in and around Santa Cruz de la Sierra

  1. Use filters to find the right car: Refine your search by selecting vehicle types and features. Whether you require an SUV for additional space, a convertible for summer drives, or an economy car for budget-friendly travel, utilize filters on Expedia to find the ideal option for your trip.
  2. Book in advance to help lower costs: Rental prices can vary based on demand, so it's advisable to reserve your car well ahead of your trip. By booking in advance, you're more likely to access lower rates and better availability, particularly during peak travel seasons.
  3. Consider a smaller car for savings: Smaller vehicles are typically more affordable to rent and easier to park in crowded areas. Mid-size rentals strike a good balance between cost, comfort, and fuel efficiency.
  4. Age guidelines: Drivers under 30 years old may encounter higher deposits or daily fees, and certain vehicle types—such as SUVs or premium models—may not be available to them. This can also apply to renters over 70 years old. Always verify the age requirements prior to booking.
  5. Check fuel policies: Some rental agreements mandate a full-to-full fuel policy, requiring you to return the car with a full tank to avoid extra charges. This is typically the best option. Other rentals may offer full-to-empty or prepaid fueling options, which are also acceptable; just ensure you return the car empty in that scenario.
  6. Save on city and airport pickups: There is often an additional fee for picking up your rental car at airports, but the convenience might make it worthwhile.
  7. Know your payment options: Many car rental companies exclusively accept credit cards for payment.
  8. Understand your insurance coverage: Car rental insurance can help you avoid unexpected expenses and provide peace of mind in case of unforeseen incidents during your trip. It's easy to add car rental insurance when booking through Expedia.
  9. Consider unlimited mileage: If you plan on taking long road trips, seek out rentals that offer unlimited mileage to prevent any additional costs.
  10. Bring your driver's license and ID: A valid driver's license is mandatory to rent a car.

Finding the cheapest car rentals in Santa Cruz de la Sierra

Using our Search Wizard

If the deals that are available on our page do not suit your needs, then enter Santa Cruz de la Sierra into the search wizard at the top of the page. We will compare all the best deals available for your car rental in Santa Cruz de la Sierra and provide you with a list of the cheapest options, with no added fees.

Renting a car in Santa Cruz de la Sierra

Pay at pickup is available, so you don’t have to worry about spending your money until you arrive at your vehicle in Santa Cruz de la Sierra. We partner with reliable partners that guarantee an enjoyable experience for solo travelers, couples, and families. Package your car with a flight or hotel to unlock even more savings from Expedia.

Expected prices in Santa Cruz de la Sierra

Prices are subject to seasonal change depending on when you decide to arrange your car rental but right now you can book .

Flexibility & Cancellation

Most car suppliers offer penalty-free cancellations, so you don’t have to worry about losing money if your plans change. To cancel your booking log into your account through the Trips portal. Click manage booking and cancel this car. If you needed to alter your booking, then you can create a new one once you have canceled.

We all love being rewarded

One Key members save 10% or more on select hotels, cars, activities and vacation rentals. Not only that, earn OneKeyCash for every dollar spent on eligible hotels, vacation rentals, flights, car rentals, and more when you book across our family of brands: Expedia, Hotels.com and VRBO. Learn more and join today.

Car classes available from Expedia in 2026

The classes of vehicles available will change depending on your chosen location.

Car Rental Information

Popular car types
SUV, Full Size, Economy
Car suppliers available
Our best deal of the day
Our second best deal of the day
Our third best deal of the day
From the airport to your hotel
Airport Transportation
From popular domestic and international airports
Airport Car Rentals

Frequently asked questions

How much is a rental car per day in Santa Cruz de la Sierra?
The cheapest daily rate in Santa Cruz de la Sierra was based on prices within the last seven days. Check out our terrific range of options, from small and affordable vehicles to cruise-in-style rides.
What happens if I need to cancel my Santa Cruz de la Sierra car reservation?
Browse through your rental policy to be certain, but nearly all prepaid reservations will receive a total refund if you advise us a minimum of six hours prior to pickup. There are some exclusions though. Your itinerary will have more details, or just jump onto our Customer Service Portal.
Where can I go on a road trip from Santa Cruz de la Sierra?
There's loads to do in Santa Cruz de la Sierra, but head farther afield and you'll find more sightseeing magic. Grab a set of wheels and you can cruise around the surrounding region at your own pace. Add these awesome destinations to your travel plan:
  • You'll discover Toledo Cathedral and countless other amazing attractions in Toledo. From Santa Cruz de la Sierra, it's around 100 miles away.
  • Next stop? It has to be Córdoba, which is around 120 miles away. Mosque–Cathedral of Córdoba is one local draw card you really shouldn't miss.
  • Make your way to Mirador de San Nicolas to discover some local nature. Pack a picnic to enjoy or just recharge your batteries in the fresh air. From Santa Cruz de la Sierra, it's about 190 miles away.
How do I find the best car rental deals in Santa Cruz de la Sierra with Expedia?
Expedia makes it easy and fast to compare rates, offers and rental companies, and to check customer reviews. Combine your Santa Cruz de la Sierra car rental with flight or hotel bookings and you'll save even more.
How old do you have to be to rent a car in Santa Cruz de la Sierra?
The minimum age to rent a car in Santa Cruz de la Sierra is 21. A surcharge for young drivers generally applies, so check before you book and budget for any extra costs. There could also be restrictions on the sorts of cars available to young drivers. For instance, some outlets will only rent out economy to medium-sized cars to young motorists. Rules may vary between providers, so be sure to read the fine print carefully.
What do you need to rent a car in Santa Cruz de la Sierra?
Renting a car in Santa Cruz de la Sierra is a cinch. Normally, all you'll need is a current driver's license and a credit card. Once you've found a great set of wheels, check your policy to ensure there are no additional requirements prior to your scheduled pickup.
What side of the road do you drive on in Santa Cruz de la Sierra?
Travelers from the States will feel quite at home cruising around Santa Cruz de la Sierra — motorists here drive on the right-hand side of the road.
What is the cheapest car rental in Santa Cruz de la Sierra?
We looked into prices over the last seven days and found that the lowest daily rate was . The second lowest price to rent a ride in Santa Cruz de la Sierra was a day. These rates were available on Expedia, with a rental starting date within the next year. Prices and availability are subject to change and additional terms apply.
Can I rent a car for a month or longer in Santa Cruz de la Sierra?
Yes, which means you won't have to rebook a rental car mid-vacation. Click on our long-term car rental deals page, enter your travel dates and lock in a ride to call your own for the length of your escape.
Where can I find a Santa Cruz de la Sierra car rental if I am younger than 25?
Age policies differ between rental companies, so you'll have to do a little research. Managed to find a Santa Cruz de la Sierra outlet that does rent to drivers under 25? Terrific! Just take note that a surcharge often applies to drivers aged between 21 and 24. The fine print of each rental car you're interested in should have all the details you need.
What insurance should I choose for my car rental in Santa Cruz de la Sierra?
After carefuly planning your road trip, don't scrimp on safety — purchase collision protection while booking your Santa Cruz de la Sierra rental car with Expedia. There are lots of advantages to this plan, including up to $35,000 in primary coverage for accident damage, theft and vandalism. Plus, with a zero-dollar deductible and 24-hour emergency assistance, you'll be able to breathe a little easier should a mishap occur.
Can I drive in Santa Cruz de la Sierra with my current driver's license?
If you don't possess a driver's license issued in Spain, then you might need to acquire an International Driving Permit (IDP) in your place of residence to be allowed to rent a car. You should also be aware that if you do need an IDP, it has no validity on its own. You'll have to show your current driver's license your passport and other forms of ID as well. Lastly, it's important that the credit card used to book the rental matches the name on your driver's license and passport. Some other things to note for international car rentals are:
  • Age restrictions: You need to be at least 25 in many countries to rent a car. If you're younger than that, it might still be possible to rent a car but you'll have to pay a Young Driver's Surcharge. Additional restrictions may also apply to the types of vehicles available to rent.
  • Driving limitations: Be sure to read the rules and regulations before you drive away. With rental cars, you usually can't cross country borders, drive onto ferries or off road with a rental vehicle.

Explore a world of travel with Expedia